ceesdekker No Further a Mystery

ceesdekker No Further a Mystery

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2009, discovery of a completely new phenotype for bacteria in narrow nanofluidic slits; and very first detection of regional protein constructions alongside DNA employing strong-state nanopores

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‘It had been merely a matter of buying up a e book on mobile biology and beginning to study. I'd originate from a planet of ultra-significant vacuums, cryostats and quantum phenomena, and now I used to be working at home temperature with molecular biology kits.

Because 2000, Dekker has shifted the principle aim of his perform toward biophysics where he scientific studies the Houses of one biomolecules and cells using the resources of nanotechnology. This variation of industry was pushed by his fascination for the exceptional operating of Organic molecular buildings, as well as because of the extensive-term viewpoint that lots of appealing discoveries is usually envisioned in this area.[5] Recent traces of exploration in his biophysics team are from the parts of:[six]

2015, discovery that condensin is actually a extremely flexible protein composition; and very first detection of DNA knots utilizing nanopores

Illustration (three) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in gray, the rim from the pore is highlighted in purple, and a 3D rendering in the movement of the DNA rod is displayed.

Length Charge of person carbon nanotubes by nanostructuring While using the scanning tunneling microscope

Instance (one) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is shown in grey, the rim in the pore is highlighted in purple, and a 3D rendering in the motion with the DNA rod is exhibited.

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Bulk-surface area coupling identifies the mechanistic link involving Min-protein styles in vivo As well as in vitro

[fourteen] In 2005 Dekker became involved with Netherlands-wide discussions about Clever Design and style, a motion that he has because Plainly distanced himself from. Dekker advocates that science and religion will not be in opposition but can be harmonized.

Cees Dekker is Distinguished College Professor at TU Delft. Experienced being a physicist, he pioneered nanotechnology with several discoveries on carbon nanotubes within the 1990s. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His recent analysis concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, particularly SMC motor protein; and (iii) building a dwelling synthetic cell from lifeless molecules. Dekker can be an elected member on the KNAW and fellow for the APS and also the IOP.

Developments in nanotechnology from the nineties created creating electronic devices from one molecules a probability. Cees Dekker recounts how his staff designed a area-temperature transistor depending on an individual carbon ceesdekker nanotube.

Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and one-molecule experiments