Helping The others Realize The Advantages Of ceesdekker
Helping The others Realize The Advantages Of ceesdekker
Blog Article
2009, discovery of a completely new phenotype for bacteria in narrow nanofluidic slits; and initial detection of neighborhood protein constructions along DNA making use of sound-condition nanopores
You will help our writer matching technique! In case you detect any publications improperly attributed to this writer, remember to register and mark matches as proper or incorrect.
Dynamics of initiation, termination and reinitiation of DNA translocation by the motor protein EcoR124I
Due to the fact 2000, Dekker has shifted the primary emphasis of his do the job in the direction of biophysics the place he research the Homes of one biomolecules and cells utilizing the tools of nanotechnology. This variation of subject was pushed by his fascination to the exceptional functioning of Organic molecular structures, together with by the lengthy-phrase point of view a large number of attention-grabbing discoveries can be expected In this particular discipline.[five] Recent traces of analysis in his biophysics group are during the areas of:[6]
This yielded a breakthrough. Within just only some months, we had been capable to evaluate transportation through an individual solitary-walled carbon nanotube. According to small-temperature experiments by a brilliant PhD university student in my group, Sander Tans (now a valued colleague and professor at Delft University of Engineering with the Energetic research lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up genuine quantum wires with quite long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes
What distinguishes biology from chemistry is that these parts together make up a residing system. The key of said daily life, I do think, lies inside the interactions, the interaction of These molecules. The large question with regard to the origin of existence remains to be unanswered. How did we ever evolve from very simple molecules in to the really complex programs we see now? We have no idea. I would like to operate on these kinds of huge, open up thoughts.’
Stream-pushed rotary motors such as windmills and water wheels generate useful procedures in human Modern society. Although examples of this sort of rotary motors also attribute prominently in mobile biology, their artificial design at the nanoscale has remained difficult. Listed here we exhibit stream-pushed rotary movement of the self-structured DNA nanostructure that is docked onto a nanopore in a thin solid-point out membrane. An elastic DNA bundle self-assembles right into a chiral conformation on phoretic docking onto the reliable-condition nanopore, and subsequently shows a sustained unidirectional rotary motion of up to twenty rev s−1.
‘You should not just think of the issues of tomorrow, and also evaluate the thoughts from the day after tomorrow’
‘The fantastically subtle way wherein things in character operate by no means ceases to amaze me. If we resolve the puzzle of how lifestyle arrived into staying, I assume that my amazement in the complexity of generation will likely have enhanced and with it my awe for your greatness of the Creator.’
Skip to principal written content Thank you for visiting character.com. You are utilizing a browser version with constrained support for CSS. To get the best practical experience, we suggest you utilize a more current browser (or flip off compatibility method in Internet Explorer).
Cees Dekker is Distinguished College Professor at TU Delft. Skilled like a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes in the nineteen nineties. Due to the fact 2000, he moved to solitary-molecule biophysics and nanobiology. His present research concentrates on (i) nanopores for protein sequencing; (ii) chromosome construction, in particular SMC motor protein; and (iii) developing a residing synthetic mobile from lifeless molecules. Dekker is surely an elected member from the KNAW and fellow into the APS and also the IOP.
2008, 1st observation of protein-coated DNA translocation by way of nanopores; solved the origin on the electrophoretic power on DNA in nanopores; discovered an important velocity increase of microtubules in electric fields; discovered an anomalous electro-hydrodynamic orientation of microtubules; and settled the origin of noise in carbon nanotubes in liquid
Instance (two) of bending configurations in 3D simulations of DNA rods on cees dekker nanopores. A percentage of the membrane is proven in gray, the rim of the pore is highlighted in crimson, in addition to a 3D rendering in the movement of the DNA rod is shown.